Across TCGA pan-cancer cohorts, GPR132 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated GPR132 data layer compared with 27 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher GPR132 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated GPR132 expression acts as an unfavorable survival marker.

SKCM, LIHC, and COAD are the cancer types where GPR132 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.098	0.343	<.001	18	view →
LIHC	OS	Median	All	0.059	0.783	<.001	6	view →
COAD	DFS	Median	III,IV	0.127	0.704	<.001	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: GPR132 tumor-vs-normal RNA expression · all GPR132 data types