GPR132

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GPR132 mutation is significantly associated with the RNA expression of many other genes, with 2,168 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR132-associated genes across cancer lineages are MIR4270, MRPS15P1, and RNA5SP60. Each is linked with GPR132 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR132-to-partner and partner-to-GPR132 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR132→partner) and Y-score (partner→GPR132) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVMIR4270 →+0.510+5.063<.001.00833
GBMMRPS15P1 →+0.101+4.203.001.00832
GBMRNA5SP60 →+0.495+4.857<.001.00532
GBMMTCO3P45 →+0.093+4.584<.001.00732
UCECRNA5SP412 →+0.552+1.797<.001.00532
UCECEDARADD →+0.936+2.616<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,168 associations by consensus.

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