Across TCGA patient cohorts, GPR132 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR132-associated genes across cancer lineages are VHL, ATM, and Caspase-7-cleavedD198. Each is linked with GPR132 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR132-to-partner and partner-to-GPR132 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR132→partner) and Y-score (partner→GPR132) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VHL →	-0.727	-1.678	.003	.021	3	2
UCEC	ATM →	-0.559	-2.247	<.001	.001	3	2
UCEC	Caspase-7-cleavedD198 →	+0.689	+1.894	.001	.030	3	2
UCEC	4E-BP1 →	+0.337	+1.730	<.001	.025	3	2
UCEC	14-3-3_beta →	-0.113	-2.432	.002	.018	3	1
UCEC	EGFR_pY1068 →	-0.184	-1.502	.045	.030	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

GPR132 survival (RNA) · tumor vs normal (RNA) · all GPR132 data types