GPR132

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GPR132 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,969 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPR132-associated GO terms across cancer lineages are Positive regulation of canonical NF-kappaB signal transduction, Extrinsic apoptotic signaling pathway via death domain receptors, and Positive regulation of proteolysis. Each is linked with GPR132 in more than 9 cancer types. Because this analysis shows association rather than direction, both GPR132-to-partner and partner-to-GPR132 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR132→partner) and Y-score (partner→GPR132) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCPositive regulation of canonical NF-kappaB signal transduction →+0.085+0.582<.001.002310
PANCREASExtrinsic apoptotic signaling pathway via death domain receptors →+0.077+0.896<.001.002310
BLOOD_LymphomaPositive regulation of proteolysis →+0.076+1.487<.001<.001310
OVARYResponse to interleukin-1 →+0.079+0.655<.001<.00139
OVARYNegative regulation of cell adhesion →+0.105+0.913<.001<.00139
OVARYApoptotic signaling pathway →+0.043+0.632.002.00539
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,969 associations by consensus.

Exploration