GPR132

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GPR132 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPR132-associated genes across cancer lineages are GPR32, HCRT, and OR51Q1. Each is linked with GPR132 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR132-to-partner and partner-to-GPR132 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR132→partner) and Y-score (partner→GPR132) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTGPR32 →+0.028+4.064.002.00331
BREASTHCRT →+0.026+4.196<.001.00631
BREASTOR51Q1 →+0.088+4.415<.001.00131
BREASTOR56B1 →+0.099+3.758<.001.00731
BREASTH2AP →+0.183+3.758<.001.00731
BREASTSLC15A5 →+0.014+3.758.002.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration