GPR107

Across TCGA pan-cancer cohorts, GPR107 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated GPR107 data layer compared with 22 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher GPR107 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated GPR107 expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

LUSC, SKCM, and UCEC are the cancer types where GPR107 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	All	0.153	0.661	.001	36	view →
SKCM	DFS	Median	All	0.229	0.740	<.001	10	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
BLCA	OS	Median	II,III,IV	1.000	0.701	.038	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

GPR107–LUSC (DFS)

Open the LUSC breakdown →