GPR107

Across TCGA pan-cancer cohorts, GPR107 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated GPR107 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher GPR107 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated GPR107 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

LSCC, HNSC, and CCRCC are the cancer types where GPR107 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	All	0.630	0.947	<.001	22	view →
HNSC	DFS	Median	II,III,IV	0.876	0.673	.004	21	view →
CCRCC	OS	Median	All	0.715	1.000	.017	14	view →
LUAD	DFS	Tertile	All	0.572	0.943	.007	9	view →
UCEC	OS	Median	All	0.973	0.840	.009	8	view →
GBM	OS	Tertile	All	0.968	0.742	.002	4	view →
PDAC	DFS	Median	IV	0.250	0.934	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

GPR107–LSCC (OS)

Open the LSCC breakdown →