Across TCGA patient cohorts, GPR1 mutation is significantly associated with the RNA expression of many other genes, with 1,847 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR1-associated genes across cancer lineages are RNU6-1213P, OR4C46, and RNU6-934P. Each is linked with GPR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR1-to-partner and partner-to-GPR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR1→partner) and Y-score (partner→GPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1213P →	+0.216	+3.761	<.001	.001	3	3
COAD	OR4C46 →	+0.179	+7.741	<.001	.009	3	2
BRCA	RNU6-934P →	+0.818	+5.203	<.001	.007	3	2
BRCA	MIR28 →	+1.033	+5.540	<.001	.004	3	2
BRCA	RNU6-120P →	+0.813	+6.866	<.001	<.001	3	2
LUAD	MIR629 →	+0.486	+5.099	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,847 associations by consensus.

Exploration

GPR1 survival (RNA) · tumor vs normal (RNA) · all GPR1 data types