Across TCGA patient cohorts, GPR1 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR1-associated genes across cancer lineages are PEA-15_pS116, eEF2, and Ku80. Each is linked with GPR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR1-to-partner and partner-to-GPR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR1→partner) and Y-score (partner→GPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PEA-15_pS116 →	+0.400	+2.584	.014	.011	3	2
UCEC	eEF2 →	+0.517	+2.584	.001	.011	3	1
UCEC	Ku80 →	+0.285	+3.713	.009	<.001	3	1
UCEC	p62 Lck ligand →	+0.367	+3.169	.015	.018	3	1
UCEC	PCNA →	+0.318	+2.584	.001	.011	3	1
UCEC	Rab25 →	-0.400	-2.584	.009	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

GPR1 survival (RNA) · tumor vs normal (RNA) · all GPR1 data types