Across TCGA cell cohorts, GPR1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GPR1-associated genes across cancer lineages are OR10G3, OR8B12, and CLEC2A. Each is linked with GPR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR1-to-partner and partner-to-GPR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR1→partner) and Y-score (partner→GPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR10G3 →	+0.063	+5.643	<.001	.002	3	1
LUNG_SCLC	OR8B12 →	+0.036	+5.029	<.001	.006	3	1
LUNG_SCLC	CLEC2A →	+0.107	+5.029	<.001	.006	3	1
LUNG_SCLC	SPATA31D1 →	+0.843	+5.643	<.001	.002	3	1
LUNG_SCLC	RD3L →	+0.018	+5.029	.004	.006	3	1
LUNG_SCLC	TEX50 →	+0.040	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

GPR1 survival (RNA) · tumor vs normal (RNA) · all GPR1 data types