GPN2

Across TCGA patient cohorts, GPN2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,530 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GPN2-associated genes across cancer lineages are KCNH1, LINC02126, and VEPH1. Each is linked with GPN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPN2-to-partner and partner-to-GPN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPN2 versus KCNH1 in HNSC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPN2→partner) and Y-score (partner→GPN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KCNH1 →	-0.466	-0.347	<.001	<.001	3	2
HNSC	LINC02126 →	-0.410	-0.228	.004	.007	3	2
OV	VEPH1 →	-0.976	-0.585	.006	.006	3	2
BRCA	CSRNP2 →	-0.407	-0.236	.001	.003	3	2
LSCC	RPUSD2 →	+0.421	+0.255	.001	.001	3	2
BRCA	TRAPPC2L →	+0.372	+0.332	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,530 associations by consensus.

GPN2 vs KCNH1 — HNSC

Explore this scatter interactively →