Across TCGA patient cohorts, GPN1 protein abundance is significantly associated with the protein abundance of many other proteins, with 9,849 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPN1-associated proteins across cancer lineages are RPAP1, EIF2B1, and UBE2O. Each is linked with GPN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GPN1-to-partner and partner-to-GPN1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPN1→partner) and Y-score (partner→GPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RPAP1 →	+0.279	+0.259	.002	.009	1	7
UCEC	EIF2B1 →	+0.177	+0.177	.001	<.001	3	4
LUAD	UBE2O →	+0.292	+0.190	<.001	<.001	3	4
CCRCC	KPNB1 →	+0.187	+0.161	<.001	.001	3	4
LSCC	POLR2C →	+0.163	+0.222	<.001	<.001	3	4
OV	ATXN2L_S496 →	+1.201	+0.407	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,849 associations by consensus.

Exploration

GPN1 survival (RNA) · tumor vs normal (RNA) · all GPN1 data types