Across TCGA cell cohorts, GPN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,066 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPN1-associated GO terms across cancer lineages are Meiotic sister chromatid cohesion, centromeric, Centromeric sister chromatid cohesion, and Positive regulation of chromosome condensation. Each is linked with GPN1 in more than 12 cancer types. Because this analysis shows association rather than direction, both GPN1-to-partner and partner-to-GPN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPN1→partner) and Y-score (partner→GPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Meiotic sister chromatid cohesion, centromeric →	+0.124	+0.631	<.001	<.001	3	13
BLOOD_Lymphoma	Centromeric sister chromatid cohesion →	+0.133	+0.773	<.001	<.001	3	13
BREAST	Positive regulation of chromosome condensation →	+0.184	+0.838	<.001	.001	3	12
BLOOD_Lymphoma	Microtubule cytoskeleton organization involved in mitosis →	+0.084	+0.771	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Establishment of mitotic spindle orientation →	+0.118	+0.948	.004	.006	3	11
CNS	Protein localization to cytoskeleton →	+0.044	+0.475	.004	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,066 associations by consensus.

Exploration

GPN1 survival (RNA) · tumor vs normal (RNA) · all GPN1 data types