GPM6BP3

Across TCGA pan-cancer cohorts, GPM6BP3 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated GPM6BP3 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher GPM6BP3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GPM6BP3 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

KIRC, UVM, and LIHC are the cancer types where GPM6BP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.224	0.632	.008	48	view →
UVM	OS	Tertile	All	0.292	0.674	.035	18	view →
LIHC	OS	Tertile	All	0.031	0.775	<.001	18	view →
ESCA	DFS	Tertile	III,IV	1.000	0.279	.035	12	view →
UCEC	DFS	Tertile	All	0.286	0.670	.016	12	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
THCA	DFS	Tertile	II,III,IV	0.621	0.907	.044	9	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

GPM6BP3–KIRC (DFS)

Open the KIRC breakdown →