GPLD1

Across TCGA patient cohorts, GPLD1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,949 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPLD1-associated genes across cancer lineages are LYVE1, MMP19, and IL6. Each is linked with GPLD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GPLD1-to-partner and partner-to-GPLD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPLD1 versus LYVE1 in BRCA, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPLD1→partner) and Y-score (partner→GPLD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LYVE1 →	+1.444	+0.579	<.001	<.001	3	7
GBM	MMP19 →	+1.313	+0.415	<.001	<.001	3	6
UCEC	IL6 →	+1.690	+0.462	<.001	<.001	3	6
OV	TGFBR2 →	+0.746	+0.556	<.001	.002	3	6
LSCC	S1PR1 →	+1.005	+0.515	<.001	<.001	3	5
OV	PDGFB →	+0.708	+0.447	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,949 associations by consensus.

GPLD1 vs LYVE1 — BRCA

Explore this scatter interactively →