GPLD1

Across TCGA cell cohorts, GPLD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,582 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPLD1-associated GO terms across cancer lineages are Response to triglyceride, C-terminal protein lipidation, and Positive regulation of DNA repair. Each is linked with GPLD1 in more than 19 cancer types. Because this analysis shows association rather than direction, both GPLD1-to-partner and partner-to-GPLD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to triglyceride grouped by GPLD1-low versus GPLD1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPLD1→partner) and Y-score (partner→GPLD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Response to triglyceride →	-0.400	-1.413	<.001	<.001	3	20
LIVER	C-terminal protein lipidation →	-0.274	-1.190	<.001	<.001	3	16
BONE	Positive regulation of DNA repair →	+0.097	+1.044	<.001	<.001	3	15
BLOOD_Leukemia	Positive regulation of double-strand break repair →	+0.067	+0.705	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of transcription initiation by RNA polymerase II →	+0.071	+0.478	<.001	<.001	3	14
STOMACH	Epigenetic regulation of gene expression →	+0.078	+0.874	.001	.006	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,582 associations by consensus.

Response to triglyceride by GPLD1 expression — LIVER

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