GPKOW

Across TCGA patient cohorts, GPKOW RNA expression is significantly associated with the protein abundance of many other proteins, with 10,211 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPKOW-associated proteins across cancer lineages are GRIPAP1, TSR2, and HUWE1. Each is linked with GPKOW in more than 5 cancer types. Because this analysis shows association rather than direction, both GPKOW-to-partner and partner-to-GPKOW results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPKOW versus GRIPAP1 in OV, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPKOW→partner) and Y-score (partner→GPKOW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GRIPAP1 →	+0.322	+0.599	.001	<.001	3	6
COAD	TSR2 →	+0.368	+0.349	<.001	.004	3	5
OV	HUWE1 →	+0.242	+0.559	<.001	<.001	3	5
LSCC	CSTF2 →	+0.210	+0.340	.005	.002	3	5
GBM	PPIB →	-0.303	-0.302	<.001	<.001	3	4
LSCC	ARHGAP25 →	-0.407	-0.323	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,211 associations by consensus.

GPKOW vs GRIPAP1 — OV

Explore this scatter interactively →