GPKOW

Across TCGA patient cohorts, GPKOW protein abundance is significantly associated with the RNA expression of many other genes, with 13,560 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPKOW-associated genes across cancer lineages are SUV39H1, JADE3, and POLA1. Each is linked with GPKOW in more than 7 cancer types. Because this analysis shows association rather than direction, both GPKOW-to-partner and partner-to-GPKOW results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPKOW versus SUV39H1 in OV, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPKOW→partner) and Y-score (partner→GPKOW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SUV39H1 →	+0.799	+0.374	<.001	<.001	3	8
GBM	JADE3 →	+0.653	+0.264	<.001	<.001	3	8
LSCC	POLA1 →	+0.608	+0.231	<.001	<.001	3	8
OV	PQBP1 →	+0.597	+0.327	.001	<.001	3	8
UCEC	RBL1 →	+0.648	+0.267	<.001	<.001	3	8
BRCA	TTK →	+1.116	+0.290	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,560 associations by consensus.

GPKOW vs SUV39H1 — OV

Explore this scatter interactively →