GPHB5

Across TCGA patient cohorts, GPHB5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,200 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GPHB5-associated GO terms across cancer lineages are Negative regulation of cell projection organization, Microtubule polymerization, and Cellular response to gamma radiation. Each is linked with GPHB5 in more than 8 cancer types. Because this analysis shows association rather than direction, both GPHB5-to-partner and partner-to-GPHB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell projection organization grouped by GPHB5-low versus GPHB5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPHB5→partner) and Y-score (partner→GPHB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of cell projection organization →	+0.049	+0.136	<.001	<.001	3	9
STAD	Microtubule polymerization →	+0.074	+0.147	<.001	<.001	3	9
STAD	Cellular response to gamma radiation →	+0.075	+0.131	<.001	<.001	3	9
STAD	Spindle organization →	+0.084	+0.154	<.001	<.001	3	9
ESCA	Regulation of establishment of planar polarity →	+0.052	+0.222	<.001	<.001	3	8
STAD	Somite development →	+0.041	+0.106	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,200 associations by consensus.

Negative regulation of cell projection organization by GPHB5 expression — STAD

Explore this box plot interactively →