GPHB5

Across TCGA patient cohorts, GPHB5 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible GPHB5-associated genes across cancer lineages are Preadipocytes, Chondrocytes, and Mesangial cells. Each is linked with GPHB5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPHB5-to-partner and partner-to-GPHB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Preadipocytes grouped by GPHB5-low versus GPHB5-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPHB5→partner) and Y-score (partner→GPHB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	Preadipocytes →	+0.051	+4.527	<.001	.017	3	1
LUSC	Chondrocytes →	+0.017	+4.694	.001	.014	3	1
UCEC	Mesangial cells →	-0.055	-2.936	.006	.036	3	1
SKCM	iDC →	-0.176	-3.163	.044	.020	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Preadipocytes by GPHB5 expression — BLCA

Explore this box plot interactively →