GPHB5

Across TCGA cell cohorts, GPHB5 RNA expression is significantly associated with the mutation status of many other genes, with 89 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible GPHB5-associated genes across cancer lineages are GAPVD1, SLC39A14, and NOVA1. Each is linked with GPHB5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPHB5-to-partner and partner-to-GPHB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPVD1 grouped by GPHB5-low versus GPHB5-high in PANCREAS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPHB5→partner) and Y-score (partner→GPHB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	GAPVD1 →	+5.000	+0.058	.006	<.001	3	2
LUNG_NSCLC_LUAD	SLC39A14 →	+4.887	+0.036	.009	.004	3	2
LUNG_NSCLC_LUAD	NOVA1 →	+3.150	+0.033	.006	<.001	3	2
LUNG_NSCLC_LUAD	CNOT11 →	+4.887	+0.070	.009	<.001	3	2
SOFT_TISSUE	TRAP1 →	+4.977	+0.097	.002	<.001	3	1
SOFT_TISSUE	CPEB2 →	+4.977	+0.097	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 89 associations by consensus.

GAPVD1 by GPHB5 expression — PANCREAS

Explore this box plot interactively →