GPER1

Across TCGA patient cohorts, GPER1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,571 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GPER1-associated proteins across cancer lineages are AQR, PAFAH1B3, and PIK3CG_S974. Each is linked with GPER1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPER1-to-partner and partner-to-GPER1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPER1 versus AQR in LSCC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPER1→partner) and Y-score (partner→GPER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AQR →	+0.196	+0.294	.001	.007	3	3
BRCA	PAFAH1B3 →	+0.318	+0.599	.003	.002	3	3
HNSC	PIK3CG_S974 →	-0.522	-0.583	<.001	.003	3	3
CCRCC	TM9SF3 →	-0.334	-1.157	<.001	<.001	3	3
LSCC	POLR1A →	+0.235	+0.375	.005	.006	3	3
HNSC	POLR1F →	+0.332	+0.603	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,571 associations by consensus.

GPER1 vs AQR — LSCC

Explore this scatter interactively →