GPD2

Across TCGA patient cohorts, GPD2 mutation is significantly associated with the RNA expression of many other genes, with 4,372 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPD2-associated genes across cancer lineages are BNIP3P1, RNA5SP247, and JKAMPP1. Each is linked with GPD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPD2-to-partner and partner-to-GPD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BNIP3P1 grouped by GPD2-low versus GPD2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPD2→partner) and Y-score (partner→GPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BNIP3P1 →	+0.553	+1.939	<.001	<.001	3	2
LUAD	RNA5SP247 →	+0.675	+3.676	.008	.007	3	2
LUAD	JKAMPP1 →	+0.057	+4.444	<.001	.006	3	2
LUAD	GRM7-AS2 →	+0.129	+3.938	<.001	.003	3	2
BLCA	IDI1P2 →	+0.046	+5.229	<.001	.002	3	2
BLCA	OLIG3 →	+1.262	+4.049	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,372 associations by consensus.

BNIP3P1 by GPD2 expression — UCEC

Explore this box plot interactively →