GPD1L

Across TCGA cell cohorts, GPD1L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,463 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible GPD1L-associated GO terms across cancer lineages are Regulation of ventricular cardiac muscle cell membrane depolarization, Negative regulation of immune response, and Tetrapyrrole biosynthetic process. Each is linked with GPD1L in more than 13 cancer types. Because this analysis shows association rather than direction, both GPD1L-to-partner and partner-to-GPD1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of ventricular cardiac muscle cell membrane depolarization grouped by GPD1L-low versus GPD1L-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPD1L→partner) and Y-score (partner→GPD1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of ventricular cardiac muscle cell membrane depolarization →	+1.219	+1.367	<.001	<.001	3	14
BREAST	Negative regulation of immune response →	-0.070	-1.224	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Tetrapyrrole biosynthetic process →	+0.069	+0.952	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Porphyrin-containing compound biosynthetic process →	+0.069	+0.952	<.001	<.001	3	9
BREAST	Branched-chain amino acid catabolic process →	+0.117	+1.561	<.001	<.001	3	9
BREAST	Regulation of tumor necrosis factor production →	-0.056	-1.156	.005	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,463 associations by consensus.

Regulation of ventricular cardiac muscle cell membrane depolarization by GPD1L expression — URINARY_TRACT

Explore this box plot interactively →