GPD1

Across TCGA patient cohorts, GPD1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,074 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GPD1-associated genes across cancer lineages are ACSM5, CHRDL1, and ASPA. Each is linked with GPD1 in more than 7 cancer types. Because this analysis shows association rather than direction, both GPD1-to-partner and partner-to-GPD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPD1 versus ACSM5 in GBM, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPD1→partner) and Y-score (partner→GPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ACSM5 →	+1.003	+0.986	<.001	<.001	3	8
BRCA	CHRDL1 →	+1.711	+1.443	<.001	<.001	3	7
GBM	ASPA →	+0.940	+0.678	<.001	<.001	3	7
OV	ALDH2 →	+1.017	+1.672	<.001	<.001	3	7
OV	PDE1B →	+0.837	+1.383	<.001	<.001	3	7
PDAC	ITIH3 →	+0.533	+0.646	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,074 associations by consensus.

GPD1 vs ACSM5 — GBM

Explore this scatter interactively →