Across TCGA cell cohorts, GPC6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,727 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GPC6-associated GO terms across cancer lineages are Cerebral cortex tangential migration, Golgi vesicle transport, and Positive regulation of protein folding. Each is linked with GPC6 in more than 9 cancer types. Because this analysis shows association rather than direction, both GPC6-to-partner and partner-to-GPC6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPC6→partner) and Y-score (partner→GPC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Cerebral cortex tangential migration →	+1.300	+2.087	.001	.001	3	10
SKIN	Golgi vesicle transport →	+0.041	+1.769	.001	.001	3	8
SOFT_TISSUE	Positive regulation of protein folding →	+0.113	+2.092	<.001	<.001	3	7
SOFT_TISSUE	Collagen biosynthetic process →	+0.223	+2.072	<.001	<.001	3	7
SKIN	Negative regulation of syncytium formation by plasma membrane fusion →	+0.057	+1.720	<.001	<.001	3	7
PANCREAS	Aldosterone metabolic process →	+1.072	+1.563	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,727 associations by consensus.

Exploration

GPC6 survival (RNA) · tumor vs normal (RNA) · all GPC6 data types