GPC6-AS1

Across TCGA pan-cancer cohorts, GPC6-AS1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of GPC6-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where GPC6-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GPC6-AS1 is over-expressed in tumor.

LIHC, LUAD, and BRCA are the cancer types where GPC6-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GPC6-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	All	+0.073	<.001	5	view →
LUAD	All	All	+0.134	.015	2	view →
BRCA	Female	All	+0.083	.048	2	view →
KIRC	Male	All	+0.024	.027	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

GPC6-AS1–LIHC

Open the LIHC breakdown →