GPC5-AS1

Across TCGA pan-cancer cohorts, GPC5-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated GPC5-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher GPC5-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GPC5-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRP and LUAD show a favorable association.

ACC, KIRP, and COAD are the cancer types where GPC5-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.458	0.899	<.001	114	view →
KIRP	OS	Median	All	0.770	0.588	<.001	100	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	81	view →
BLCA	DFS	Tertile	III,IV	0.231	0.512	.002	63	view →
READ	OS	Tertile	All	0.069	0.910	<.001	54	view →
LUAD	OS	Median	All	0.865	0.778	.001	42	view →
PCPG	DFS	Tertile	All	0.567	0.890	.001	33	view →
MESO	OS	Tertile	All	0.298	0.571	.006	27	view →
SKCM	DFS	Tertile	IV	0.036	0.433	<.001	21	view →
LGG	OS	Tertile	All	0.841	0.913	.011	19	view →
LAML	DFS	Tertile	All	0.683	0.326	.045	12	view →
PAAD	DFS	Tertile	All	0.491	0.270	.006	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

GPC5-AS1–ACC (OS)

Open the ACC breakdown →