Across TCGA patient cohorts, GPC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,968 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPC2-associated proteins across cancer lineages are HDAC2, TIA1, and CLINT1. Each is linked with GPC2 in more than 7 cancer types. Because this analysis shows association rather than direction, both GPC2-to-partner and partner-to-GPC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPC2→partner) and Y-score (partner→GPC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HDAC2 →	+0.327	+1.136	<.001	<.001	3	8
HNSC	TIA1 →	+0.378	+0.609	<.001	.003	2	8
OV	CLINT1 →	-0.289	-0.860	<.001	.002	3	7
OV	DNMT3A →	+0.696	+0.938	<.001	<.001	3	7
OV	STMN1 →	+0.708	+0.691	<.001	.002	3	6
LSCC	MEX3A_S462 →	+1.057	+0.684	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,968 associations by consensus.

Exploration

GPC2 survival (RNA) · tumor vs normal (RNA) · all GPC2 data types