Across TCGA cell cohorts, GPC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,146 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPC2-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Positive regulation of DNA repair, and Regulation of nucleotide-excision repair. Each is linked with GPC2 in more than 14 cancer types. Because this analysis shows association rather than direction, both GPC2-to-partner and partner-to-GPC2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPC2→partner) and Y-score (partner→GPC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of double-strand break repair →	+0.071	+1.275	.006	<.001	3	15
BONE	Positive regulation of DNA repair →	+0.093	+2.458	<.001	<.001	3	15
STOMACH	Regulation of nucleotide-excision repair →	+0.126	+1.593	.007	<.001	3	15
STOMACH	Epigenetic regulation of gene expression →	+0.081	+1.648	<.001	<.001	3	15
STOMACH	Positive regulation of myoblast differentiation →	+0.132	+1.257	<.001	.002	3	15
BONE	RNA localization →	+0.106	+2.037	.006	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,146 associations by consensus.

Exploration

GPC2 survival (RNA) · tumor vs normal (RNA) · all GPC2 data types