GPC1

Across TCGA patient cohorts, GPC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,445 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPC1-associated proteins across cancer lineages are TUBB6, ITGB5, and P4HA2. Each is linked with GPC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GPC1-to-partner and partner-to-GPC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPC1 versus TUBB6 in OV, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPC1→partner) and Y-score (partner→GPC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TUBB6 →	+0.439	+1.115	<.001	<.001	3	5
LSCC	ITGB5 →	+0.589	+1.462	<.001	<.001	3	5
PDAC	P4HA2 →	+0.562	+0.406	<.001	<.001	3	4
LSCC	PLCL2 →	-0.319	-1.044	<.001	<.001	3	4
LSCC	PLCL2_S1113 →	-0.583	-0.774	<.001	<.001	3	4
GBM	SYNJ1 →	-0.295	-0.477	.002	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,445 associations by consensus.

GPC1 vs TUBB6 — OV

Explore this scatter interactively →