GPBP1L1

Across TCGA patient cohorts, GPBP1L1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,933 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GPBP1L1-associated genes across cancer lineages are FXYD2, RPS12P16, and OTUD1. Each is linked with GPBP1L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPBP1L1-to-partner and partner-to-GPBP1L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPBP1L1 versus FXYD2 in GBM, with a Pearson correlation of -0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPBP1L1→partner) and Y-score (partner→GPBP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FXYD2 →	-0.975	-0.386	.007	.003	3	3
GBM	RPS12P16 →	-0.885	-0.377	.003	.004	3	3
OV	OTUD1 →	-0.715	-0.983	.002	.003	3	2
LSCC	AKR1C5P →	-0.870	-0.145	.005	.009	3	2
LSCC	H3C11 →	+1.031	+0.163	<.001	<.001	3	2
LSCC	SS18L2P1 →	-0.240	-0.171	.008	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,933 associations by consensus.

GPBP1L1 vs FXYD2 — GBM

Explore this scatter interactively →