GPBP1L1

Across TCGA cell cohorts, GPBP1L1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible GPBP1L1-associated genes across cancer lineages are OR10AG1, OR2G6, and OR8K3. Each is linked with GPBP1L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPBP1L1-to-partner and partner-to-GPBP1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10AG1 grouped by GPBP1L1-low versus GPBP1L1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPBP1L1→partner) and Y-score (partner→GPBP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR10AG1 →	+0.013	+5.169	<.001	.005	3	1
BREAST	OR2G6 →	+0.016	+5.169	<.001	.005	3	1
BREAST	OR8K3 →	+0.109	+5.781	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR10AG1 by GPBP1L1 expression — BREAST

Explore this box plot interactively →