Across TCGA patient cohorts, GPATCH3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,407 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPATCH3-associated proteins across cancer lineages are NUDC, ARID1A, and RPA1. Each is linked with GPATCH3 in more than 6 cancer types. Because this analysis shows association rather than direction, both GPATCH3-to-partner and partner-to-GPATCH3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPATCH3→partner) and Y-score (partner→GPATCH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NUDC →	+0.366	+0.582	<.001	<.001	3	7
LSCC	ARID1A →	+0.317	+0.397	<.001	<.001	3	7
LSCC	RPA1 →	+0.464	+0.483	<.001	<.001	3	7
LSCC	RCC2 →	+0.380	+0.341	<.001	<.001	3	6
GBM	DNAJC8 →	+0.270	+0.372	.002	<.001	3	6
BRCA	PPP1R8 →	+0.228	+0.540	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,407 associations by consensus.

Exploration

GPATCH3 survival (RNA) · tumor vs normal (RNA) · all GPATCH3 data types