Across TCGA patient cohorts, GPATCH3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,900 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPATCH3-associated genes across cancer lineages are SNF8, NOL7, and NEK6. Each is linked with GPATCH3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPATCH3-to-partner and partner-to-GPATCH3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPATCH3→partner) and Y-score (partner→GPATCH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SNF8 →	+0.683	+0.696	.001	.004	3	2
LSCC	NOL7 →	+0.661	+0.523	.003	.001	3	2
LUAD	NEK6 →	-0.668	-0.349	.002	.001	3	2
LUAD	ELF1 →	-0.510	-0.406	.002	.002	3	2
LUAD	SEC24AP1 →	-1.268	-0.345	.001	.003	3	2
LUAD	H4C4 →	+1.566	+0.359	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,900 associations by consensus.

Exploration

GPATCH3 survival (RNA) · tumor vs normal (RNA) · all GPATCH3 data types