Across TCGA cell cohorts, GPATCH3 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GPATCH3-associated genes across cancer lineages are MS4A12, FCGR3B, and IQCF6. Each is linked with GPATCH3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPATCH3-to-partner and partner-to-GPATCH3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPATCH3→partner) and Y-score (partner→GPATCH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	MS4A12 →	+0.064	+5.312	<.001	<.001	3	1
LARGE_INTESTINE	FCGR3B →	+0.174	+4.467	<.001	.004	3	1
LARGE_INTESTINE	IQCF6 →	+0.322	+4.467	<.001	.004	3	1
BLOOD_Lymphoma	CSTL1 →	+0.535	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	NEUROG1 →	+0.006	+5.643	<.001	.002	3	1
LUNG_SCLC	KRTAP9-7 →	+0.055	+4.643	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

GPATCH3 survival (RNA) · tumor vs normal (RNA) · all GPATCH3 data types