GPATCH1

Across TCGA cell cohorts, GPATCH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,835 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPATCH1-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Regulation of DNA-templated transcription initiation, and Regulation of transcription initiation by RNA polymerase II. Each is linked with GPATCH1 in more than 14 cancer types. Because this analysis shows association rather than direction, both GPATCH1-to-partner and partner-to-GPATCH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by GPATCH1-low versus GPATCH1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPATCH1→partner) and Y-score (partner→GPATCH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.068	+0.682	.001	<.001	3	15
STOMACH	Regulation of DNA-templated transcription initiation →	+0.067	+1.149	<.001	<.001	3	15
STOMACH	Regulation of transcription initiation by RNA polymerase II →	+0.066	+1.095	<.001	<.001	3	15
LUNG_SCLC	Spliceosomal complex assembly →	+0.104	+0.586	<.001	.006	3	15
BONE	RNA localization →	+0.101	+0.692	<.001	<.001	3	15
STOMACH	Negative regulation of myoblast fusion →	+0.110	+0.777	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,835 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by GPATCH1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →