GPAT3

Across TCGA patient cohorts, GPAT3 mutation is significantly associated with the RNA expression of many other genes, with 1,199 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPAT3-associated genes across cancer lineages are CIDECP1, HSPA6, and TPMTP3. Each is linked with GPAT3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPAT3-to-partner and partner-to-GPAT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CIDECP1 grouped by GPAT3-low versus GPAT3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPAT3→partner) and Y-score (partner→GPAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CIDECP1 →	+0.279	+1.781	.001	.008	3	3
UCEC	HSPA6 →	+0.939	+1.523	<.001	.008	3	3
LUAD	TPMTP3 →	+0.033	+4.303	.005	.009	3	2
LUAD	IGLV3-2 →	+1.032	+4.093	<.001	.005	3	2
UCEC	PANO1 →	+0.348	+1.970	<.001	.008	3	2
UCEC	UHRF1 →	+0.576	+1.534	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,199 associations by consensus.

CIDECP1 by GPAT3 expression — UCEC

Explore this box plot interactively →