GPAT3

Across TCGA cell cohorts, GPAT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,149 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GPAT3-associated GO terms across cancer lineages are Regulation of plasminogen activation, Intestinal lipid absorption, and Uridine metabolic process. Each is linked with GPAT3 in more than 9 cancer types. Because this analysis shows association rather than direction, both GPAT3-to-partner and partner-to-GPAT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of plasminogen activation grouped by GPAT3-low versus GPAT3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPAT3→partner) and Y-score (partner→GPAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of plasminogen activation →	+0.267	+1.874	.002	<.001	3	10
SOFT_TISSUE	Intestinal lipid absorption →	+0.318	+2.243	<.001	<.001	3	9
LUNG_SCLC	Uridine metabolic process →	+1.328	+1.588	<.001	.002	3	9
LUNG_SCLC	Pyrimidine ribonucleoside metabolic process →	+1.328	+1.588	<.001	.002	3	9
OVARY	Positive regulation of bone resorption →	+0.196	+1.926	<.001	<.001	3	9
SOFT_TISSUE	Positive regulation of calcium ion transport into cytosol →	+0.286	+1.871	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,149 associations by consensus.

Regulation of plasminogen activation by GPAT3 expression — BONE

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