GPAT3

Across TCGA cell cohorts, GPAT3 mutation is significantly associated with the mutation status of many other genes, with 717 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPAT3-associated genes across cancer lineages are MARCHF1, GIMAP7, and CACNG5. Each is linked with GPAT3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPAT3-to-partner and partner-to-GPAT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MARCHF1 grouped by GPAT3-low versus GPAT3-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPAT3→partner) and Y-score (partner→GPAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	MARCHF1 →	+5.502	+5.502	.003	.003	1	3
SOFT_TISSUE	GIMAP7 →	+5.502	+5.502	.003	.003	1	3
SOFT_TISSUE	CACNG5 →	+4.502	+5.066	.007	.007	1	3
BLOOD_Lymphoma	ARHGEF7 →	+4.014	+4.969	.008	.008	1	2
BLOOD_Lymphoma	TANGO6 →	+4.429	+5.247	.005	.005	1	2
BLOOD_Lymphoma	CRHR2 →	+4.014	+4.969	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 717 associations by consensus.

MARCHF1 by GPAT3 expression — SOFT_TISSUE

Explore this box plot interactively →