Across TCGA patient cohorts, GPAT2 mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPAT2-associated genes across cancer lineages are p27_pT198, 14-3-3_beta, and eEF2. Each is linked with GPAT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPAT2-to-partner and partner-to-GPAT2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPAT2→partner) and Y-score (partner→GPAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p27_pT198 →	+0.082	+1.807	.022	.025	3	2
UCEC	14-3-3_beta →	-0.087	-1.308	.009	.030	3	1
UCEC	eEF2 →	+0.293	+1.321	.014	.029	3	1
UCEC	EGFR_pY1068 →	-0.219	-1.874	.009	.002	3	1
UCEC	eIF4G →	+0.250	+1.584	.016	.009	3	1
UCEC	A-Raf_pS299 →	-0.089	-1.700	.026	.042	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration

GPAT2 survival (RNA) · tumor vs normal (RNA) · all GPAT2 data types