Across TCGA pan-cancer cohorts, GPANK1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated GPANK1 data layer compared with 23 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher GPANK1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated GPANK1 expression acts as an unfavorable survival marker.

STAD, LUSC, and KIRP are the cancer types where GPANK1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	II,III,IV	0.153	0.677	<.001	33	view →
LUSC	OS	Median	III,IV	0.001	0.684	<.001	24	view →
KIRP	OS	Median	All	0.270	0.904	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: GPANK1 tumor-vs-normal RNA expression · all GPANK1 data types