Across TCGA pan-cancer cohorts, GPANK1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated GPANK1 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher GPANK1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GPANK1 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

PDAC, LSCC, and LUAD are the cancer types where GPANK1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.201	0.861	.038	8	view →
LSCC	DFS	Tertile	II,III,IV	0.190	0.892	.024	5	view →
LUAD	DFS	Median	All	0.866	0.342	.007	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: GPANK1 tumor-vs-normal RNA expression · all GPANK1 data types