Across TCGA patient cohorts, GPANK1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,053 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPANK1-associated genes across cancer lineages are MEFV, FCGR3B, and CEACAM3. Each is linked with GPANK1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPANK1-to-partner and partner-to-GPANK1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPANK1→partner) and Y-score (partner→GPANK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MEFV →	+1.174	+0.516	<.001	.001	3	3
UCEC	FCGR3B →	+1.899	+1.330	<.001	<.001	3	3
UCEC	CEACAM3 →	+0.755	+1.184	<.001	<.001	3	3
UCEC	MIR223HG →	+1.422	+1.546	<.001	<.001	3	3
HNSC	CD22 →	+0.667	+0.878	<.001	.002	3	2
LSCC	GNAL →	-0.525	-0.705	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,053 associations by consensus.

Exploration

GPANK1 survival (RNA) · tumor vs normal (RNA) · all GPANK1 data types