GPANK1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GPANK1 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPANK1-associated genes across cancer lineages are Mesangial cells, CD8+ T-cells, and CMP. Each is linked with GPANK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPANK1-to-partner and partner-to-GPANK1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPANK1→partner) and Y-score (partner→GPANK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCMesangial cells →+0.021+3.215.036.02131
UCECCD8+ T-cells →+0.020+2.260<.001.03731
UCECCMP →-0.031-3.169.044.01931
UCECMelanocytes →-0.012-2.903.022.03721
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration