Across TCGA patient cohorts, GPAA1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,872 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GPAA1-associated genes across cancer lineages are CCDC69, GSS, and RPN2. Each is linked with GPAA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both GPAA1-to-partner and partner-to-GPAA1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPAA1→partner) and Y-score (partner→GPAA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCDC69 →	-1.054	-0.564	<.001	<.001	3	6
BRCA	GSS →	+0.552	+0.479	<.001	<.001	3	4
BRCA	RPN2 →	+0.437	+0.442	.002	.004	3	4
LUAD	TM7SF2 →	+0.830	+0.370	<.001	<.001	3	4
UCEC	ARHGEF10L →	-0.858	-0.596	<.001	<.001	3	4
HNSC	VSIR →	-0.821	-0.269	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,872 associations by consensus.

Exploration

GPAA1 survival (RNA) · tumor vs normal (RNA) · all GPAA1 data types