Across TCGA patient cohorts, GPAA1 mutation is significantly associated with the RNA expression of many other genes, with 496 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPAA1-associated genes across cancer lineages are MIR519A1, ZIK1P1, and RNU6-976P. Each is linked with GPAA1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPAA1-to-partner and partner-to-GPAA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPAA1→partner) and Y-score (partner→GPAA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR519A1 →	+0.668	+4.822	<.001	.006	3	3
UCEC	ZIK1P1 →	+0.087	+2.331	.005	.002	3	3
UCEC	RNU6-976P →	+0.371	+3.220	<.001	.005	3	3
CESC	MIR609 →	+0.507	+4.669	<.001	.007	3	2
CESC	MIR4673 →	+0.771	+5.060	<.001	.001	3	2
COAD	RNU1-14P →	+0.475	+4.807	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 496 associations by consensus.

Exploration

GPAA1 survival (RNA) · tumor vs normal (RNA) · all GPAA1 data types