Across TCGA cell cohorts, GPAA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,305 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GPAA1-associated GO terms across cancer lineages are Protein retention in ER lumen, Regulation of amyloid precursor protein biosynthetic process, and Assembly of actomyosin apparatus involved in cytokinesis. Each is linked with GPAA1 in more than 12 cancer types. Because this analysis shows association rather than direction, both GPAA1-to-partner and partner-to-GPAA1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPAA1→partner) and Y-score (partner→GPAA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Protein retention in ER lumen →	+0.157	+0.899	<.001	<.001	3	13
LUNG_NSCLC_LUAD	Regulation of amyloid precursor protein biosynthetic process →	+0.098	+0.567	<.001	<.001	3	10
SKIN	Assembly of actomyosin apparatus involved in cytokinesis →	+0.157	+0.785	.001	<.001	3	10
SKIN	Actomyosin contractile ring assembly →	+0.157	+0.785	.001	<.001	3	10
LUNG_SCLC	Protein linear polyubiquitination →	+0.136	+0.731	.003	.004	2	11
BLOOD_Lymphoma	Negative regulation of autophagy →	+0.039	+0.693	.001	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,305 associations by consensus.

Exploration

GPAA1 survival (RNA) · tumor vs normal (RNA) · all GPAA1 data types