Across TCGA cell cohorts, GPAA1 mutation is significantly associated with the RNA expression of many other genes, with 1,488 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPAA1-associated genes across cancer lineages are MAGEE2, LUZP2, and OR10R2. Each is linked with GPAA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPAA1-to-partner and partner-to-GPAA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPAA1→partner) and Y-score (partner→GPAA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MAGEE2 →	+0.254	+3.855	<.001	.007	3	1
BLOOD_Leukemia	LUZP2 →	+0.027	+3.855	<.001	.007	3	1
BLOOD_Leukemia	OR10R2 →	+1.939	+3.551	<.001	.009	3	1
LUNG_NSCLC_LUAD	SLC5A7 →	+0.081	+3.977	<.001	.005	3	1
LUNG_NSCLC_LUAD	USP29 →	+0.009	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	AKAP4 →	+0.010	+3.544	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,488 associations by consensus.

Exploration

GPAA1 survival (RNA) · tumor vs normal (RNA) · all GPAA1 data types