GP9

Across TCGA patient cohorts, GP9 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,033 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GP9-associated GO terms across cancer lineages are Mesangial cell differentiation, Regulation of vascular permeability, and Negative regulation of Notch signaling pathway. Each is linked with GP9 in more than 15 cancer types. Because this analysis shows association rather than direction, both GP9-to-partner and partner-to-GP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesangial cell differentiation grouped by GP9-low versus GP9-high in PCPG.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GP9→partner) and Y-score (partner→GP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PCPG	Mesangial cell differentiation →	+0.103	+0.362	<.001	<.001	3	16
ESCA	Regulation of vascular permeability →	+0.052	+0.225	<.001	.001	3	15
ESCA	Negative regulation of Notch signaling pathway →	+0.048	+0.237	<.001	<.001	2	16
STAD	Renal absorption →	+0.056	+0.116	<.001	<.001	3	15
LAML	Nitric oxide transport →	+0.150	+1.130	<.001	<.001	3	15
PCPG	Renal system vasculature development →	+0.057	+0.307	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,033 associations by consensus.

Mesangial cell differentiation by GP9 expression — PCPG

Explore this box plot interactively →